Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R011608 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
![Anti-RNF115 Rabbit mAb [67K83M50]](https://files.epizyme.cn:5005/uploads/products/202507/R011608-1.png)
| Product Name | Anti-RNF115 Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 67K83M50 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthesized peptide derived from human RNF115 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | BCA2; Breast cancer associated gene 2; CL469780; E3 ubiquitin-protein ligase RNF115; Rabring 7; RING finger protein 115; RN115_HUMAN; RNF115; Zinc finger protein 364; ZNF364. |
|---|---|
| Calculated MW | Calculated MW: 34 kDa; Observed MW: 34 kDa |
| Uniprot ID | Q9Y4L5 |
| Gene ID | 27246 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-RNF115 Rabbit mAb [67K83M50] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | E3 ubiquitin-protein ligase that mediates E2-dependent, 'Lys-48'- and/or 'Lys-63'-linked polyubiquitination of substrates and may play a role in diverse biological processes. Through their polyubiquitination, may play a role in the endosomal trafficking and degradation of membrane receptors including EGFR, FLT3, MET and CXCR4. |
|---|
| Cellular Location | Cytoplasm > cytosol. The GTP-bound form of RAB7A recruits RNF115 from the cytosol onto late endosomes/lysosomes. |
|---|
| Tissue Location | Expressed at extremely low levels in normal breast, prostate, lung, colon. Higher levels of expression are detected in heart, skeletal muscle, testis as well as in breast and prostate cancer cells. |
|---|
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