Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R021750 | ||
| 20µL | ¥738.00 | |
| 50µL | ¥1380.00 | |
| 100µL | ¥2280.00 |
立即购买
![[KD Validated] Anti-PIK3R1 Rabbit mAb [79G03D56]](https://files.epizyme.cn:5005/uploads/products/202604/R021750-FCM-1.png)
![[KD Validated] Anti-PIK3R1 Rabbit mAb [79G03D56]](https://files.epizyme.cn:5005/uploads/products/202604/R021750-WB-1.png)
![[KD Validated] Anti-PIK3R1 Rabbit mAb [79G03D56]](https://files.epizyme.cn:5005/uploads/products/202604/R021750-WB-KD-1.png)
| Product Name | [KD Validated] Anti-PIK3R1 Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, FC |
| Dilution | WB 1:2,000~1:10,000; FC 1:200~1:2,000 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 79G03D56 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthesized peptide derived from human PI3 Kinase p85 alpha |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | PIK3R1; Phosphoinositide-3-Kinase Regulatory Subunit 1; GRB1; P85-ALPHA; P85; Phosphatidylinositol 3-Kinase 85 KDa Regulatory Subunit Alpha; Phosphoinositide-3-Kinase, Regulatory Subunit 1 (Alpha); Phosphatidylinositol 3-Kinase Regulatory Subunit Alpha; Phosphoinositide-3-Kinase Regulatory Subunit Alpha; PtdIns-3-Kinase Regulatory Subunit Alpha; Growth Factor Receptor Bound 1; PI3K Regulatory Subunit Alpha; PI3-Kinase Subunit P85-Alpha; PI3 Kinase-Associated P85; P85alpha; Phosphatidylinositol 3-Kinase, Regulatory Subunit, Polypeptide 1 (P85 Alpha); Phosphatidylinositol 3-Kinase-Associated P-85 Alpha; PtdIns-3-Kinase Regulatory Subunit P85-Alpha; PI3-Kinase Regulatory Subunit Alpha; P85ALPHA; IMD36; AGM7. |
|---|---|
| Molecular weight | Calculated MW: 84 kDa; Observed MW: 75 kDa |
| Uniprot ID | P27986 |
| Gene ID | 5295 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 12 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | [KD Validated] Anti-PIK3R1 Rabbit mAb [79G03D56] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. |
|---|
| Tissue Location | Isoform 2 is expressed in skeletal muscle and brain, and at lower levels in kidney and cardiac muscle. Isoform 2 and isoform 4 are present in skeletal muscle (at protein level). |
|---|
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