Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R020573 | ||
| 20µL | ¥738.00 | |
| 50µL | ¥1380.00 | |
| 100µL | ¥2280.00 |
立即购买
![[KD Validated] Anti-NEDD4 Rabbit mAb [66F85A89]](https://files.epizyme.cn:5005/uploads/products/202604/R020573-WB-1.png)
![[KD Validated] Anti-NEDD4 Rabbit mAb [66F85A89]](https://files.epizyme.cn:5005/uploads/products/202604/R020573-WB-KD-1.png)
| Product Name | [KD Validated] Anti-NEDD4 Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB |
| Dilution | WB 1:500~1:2,500 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 66F85A89 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant protein of human NEDD4 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | NEDD4; NEDD4 E3 Ubiquitin Protein Ligase; NEDD4-1; RPF1; KIAA0093; Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase; Cell Proliferation-Inducing Gene 53 Protein; HECT-Type E3 Ubiquitin Transferase NEDD4; E3 Ubiquitin-Protein Ligase NEDD4; Receptor-Potentiating Factor 1; MGC176705; Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 4; Neural Precursor Cell Expressed, Developmentally Down-Regulated 4; EC 2.3.2.26; EC 6.3.2; NEDD-4. |
|---|---|
| Molecular weight | Calculated MW: 149 kDa; Observed MW: 130 kDa |
| Uniprot ID | P46934 |
| Gene ID | 4734 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 12 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | [KD Validated] Anti-NEDD4 Rabbit mAb [66F85A89] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity. |
|---|
| Cellular Location | Cytoplasm. Cell membrane. Recruited to the plasma membrane by GRB10. Once complexed with GRB10 and IGF1R, follows IGF1R internalization, remaining associated with early endosomes. Uncouples from IGF1R-containing endosomes before the sorting of the receptor to the lysosomal compartment (By similarity). May be recruited to exosomes by NDFIP1. |
|---|
总篇数：加载中...
总影响因子：加载中...
最高影响因子：加载中...
上海市闵行区新骏环路760号1号楼3层
400-058-8030
技术支持(电话/微信)：
张老师 18217238522
罗老师 15021027255
李老师 18301721288
如有任何关于雅酶产品问题
欢迎来信咨询
雅酶微信公众号
Copyright © 2023上海雅酶生物医药科技有限公司（Epizyme Biotech）
沪ICP备2021002422号
