Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R020190 | ||
| 20µL | ¥738.00 | |
| 50µL | ¥1380.00 | |
| 100µL | ¥2280.00 |
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![[KO Validated] Anti-FKBP4 Rabbit mAb [19R36R24]](https://files.epizyme.cn:5005/uploads/products/202604/R020190-FCM-1.png)
![[KO Validated] Anti-FKBP4 Rabbit mAb [19R36R24]](https://files.epizyme.cn:5005/uploads/products/202604/R020190-ICC-1.png)
![[KO Validated] Anti-FKBP4 Rabbit mAb [19R36R24]](https://files.epizyme.cn:5005/uploads/products/202604/R020190-WB-1.png)
![[KO Validated] Anti-FKBP4 Rabbit mAb [19R36R24]](https://files.epizyme.cn:5005/uploads/products/202604/R020190-WB-KO-1.png)
| Product Name | [KO Validated] Anti-FKBP4 Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, FC, IF (Cell)/ICC |
| Dilution | WB 1:2,000~1:10,000; FC 1:200~1:2,000; IF 1:100~1:1,000 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 19R36R24 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthesized peptide derived from human FKBP52 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | FKBP4; FKBP Prolyl Isomerase 4; FKBP59; FKBP52; Peptidyl-Prolyl Cis-Trans Isomerase FKBP4; FK506 Binding Protein 4, 59kDa; EC 5.2.1.8; Rotamase; FKBP51; HBI; T-Cell FK506-Binding Protein, 59kD; Peptidylprolyl Cis-Trans Isomerase; FK506-Binding Protein 4 (59kD); 51 KDa FK506-Binding Protein; 52 KDa FK506-Binding Protein; HSP Binding Immunophilin; HSP-Binding Immunophilin; FK506 Binding; Protein 4; FK506-Binding Protein 4; 59 KDa Immunophilin; Immunophilin FKBP52; PPIase FKBP4; 52 KDa; FKBP; FKBP-52; PPIase; FKBP-4; Hsp56; P52; P59. |
|---|---|
| Molecular weight | Calculated MW: 52 kDa; Observed MW: 52 kDa |
| Uniprot ID | Q02790 |
| Gene ID | 2288 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 12 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | [KO Validated] Anti-FKBP4 Rabbit mAb [19R36R24] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy. The human genome contains several non-transcribed pseudogenes similar to this gene. [provided by RefSeq, Sep 2008] |
|---|
| Cellular Location | Cytoplasm > cytosol. Nucleus. Cytoplasm > cytoskeleton. |
|---|
| Tissue Location | Widely expressed. |
|---|
总篇数：加载中...
总影响因子：加载中...
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