Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R020068 | ||
| 20µL | ¥738.00 | |
| 50µL | ¥1380.00 | |
| 100µL | ¥2280.00 |
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![[KD Validated] Anti-PIAS1 Rabbit mAb [12G79N18]](https://files.epizyme.cn:5005/uploads/products/202604/R020068-WB-1.png)
![[KD Validated] Anti-PIAS1 Rabbit mAb [12G79N18]](https://files.epizyme.cn:5005/uploads/products/202604/R020068-WB-KD-1.png)
| Product Name | [KD Validated] Anti-PIAS1 Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB |
| Dilution | WB 1:1,000~1:5,000 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 12G79N18 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthesized peptide derived from human PIAS1 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | PIAS1; Protein Inhibitor Of Activated STAT 1; GBP; GU/RH-II; DDXBP1; ZMIZ3; DEAD/H (Asp-Glu-Ala-Asp/His) Box Binding Protein 1; Protein Inhibitor Of Activated STAT Protein 1; Zinc Finger, MIZ-Type Containing 3; E3 SUMO-Protein Transferase PIAS1; RNA Helicase II-Binding Protein; E3 SUMO-Protein Ligase PIAS1; DEAD/H Box-Binding Protein 1; Gu-Binding Protein; AR Interacting Protein; EC 2.3.2.-. |
|---|---|
| Molecular weight | Calculated MW: 72 kDa; Observed MW: 76 kDa |
| Uniprot ID | O75925 |
| Gene ID | 8554 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 12 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | [KD Validated] Anti-PIAS1 Rabbit mAb [12G79N18] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. |
|---|
| Cellular Location | Nucleus speckle. Interaction with CSRP2 may induce a partial redistribution along the cytoskeleton. |
|---|
| Tissue Location | Expressed in numerous tissues with highest level in testis. |
|---|
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