Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R020041 | ||
| 20µL | ¥738.00 | |
| 50µL | ¥1380.00 | |
| 100µL | ¥2280.00 |
立即购买
![[KO Validated] Anti-SIRT1 Rabbit mAb [60N24J14]](https://files.epizyme.cn:5005/uploads/products/202604/R020041-WB-KO-1.png)
![[KO Validated] Anti-SIRT1 Rabbit mAb [60N24J14]](https://files.epizyme.cn:5005/uploads/products/202604/R020041-WB-1.png)
| Product Name | [KO Validated] Anti-SIRT1 Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB |
| Dilution | WB 1:1,000~1:5,000 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 60N24J14 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthesized peptide derived from human Phospho-SIRT1 (S47) |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | SIRT1; Sirtuin; SIR2L1; NAD-Dependent Protein Deacetylase Sirtuin-1; NAD-Dependent Protein Deacylase Sirtuin-1; Regulatory Protein SIR2 Homolog 1; SIR2-Like Protein 1; Sirtuin (Silent Mating Type Information Regulation 2, S. Cerevisiae, Homolog); Sirtuin (Silent Mating Type Information Regulation 2 Homolog) 1 (S. Cerevisiae); Sirtuin Type 1; EC 2.3.1.286; EC 2.3.1.- ; SIR2alpha; HSIRT1; HSIR2; SIR2. |
|---|---|
| Molecular weight | Calculated MW: 82 kDa; Observed MW: 120 kDa |
| Uniprot ID | Q96EB6 |
| Gene ID | 23411 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 12 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | [KO Validated] Anti-SIRT1 Rabbit mAb [60N24J14] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. |
|---|
| Cellular Location | Cytoplasm. Mitochondrion and Nucleus, PML body. Cytoplasm. Nucleus. Recruited to the nuclear bodies via its interaction with PML (PubMed:12006491). Colocalized with APEX1 in the nucleus (PubMed:19934257). May be found in nucleolus, nuclear euchromatin, heterochromatin and inner membrane (PubMed:15469825). Shuttles between nucleus and cytoplasm (By similarity). Colocalizes in the nucleus with XBP1 isoform 2 (PubMed:20955178). |
|---|
| Tissue Location | Widely expressed. |
|---|
总篇数：加载中...
总影响因子：加载中...
最高影响因子：加载中...
上海市闵行区新骏环路760号1号楼3层
400-058-8030
技术支持(电话/微信)：
张老师 18217238522
罗老师 15021027255
李老师 18301721288
如有任何关于雅酶产品问题
欢迎来信咨询
雅酶微信公众号
Copyright © 2023上海雅酶生物医药科技有限公司（Epizyme Biotech）
沪ICP备2021002422号
