Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R016132 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-Tau 4R Rabbit mAb [67K76M08]](https://cdn.epizyme.cn/uploads/products/202601/R016132-1.png?v=20260129153714)
![Anti-Tau 4R Rabbit mAb [67K76M08]](https://cdn.epizyme.cn/uploads/products/202601/R016132-2.png?v=20260129153714)
![Anti-Tau 4R Rabbit mAb [67K76M08]](https://cdn.epizyme.cn/uploads/products/202601/R016132-3.png?v=20260129153714)
![Anti-Tau 4R Rabbit mAb [67K76M08]](https://cdn.epizyme.cn/uploads/products/202601/R016132-4.png?v=20260129153714)
| Product Name | Anti-Tau 4R Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, IHC-P/IF (Tissue-P), ELISA |
| Dilution | WB 1:1,000~1:2,000; IHC-P 1:100~1:200; IF 1:100~1:200 |
| Reactivity | Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 67K76M08 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthesized peptide derived from human Tau 4R |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | tau; DDPAC; FTD1; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; Tau-PHF6; tau-40; Mtapt; PHF-tau; MAPT_0N4R; MAPT_1N4R; MAPT_2N4R; RNPTAU; pTau; TAU_BOVIN; MAPT; Neurofibrillary tangle protein; Paired helical filament-tau (PHF-tau); TAU_HUMAN; TAU_MOUSE; TAU_RAT. |
|---|---|
| Molecular weight | Calculated MW: 79 kDa; Observed MW: 50-80 kDa |
| Uniprot ID | P10636-6 , P10636-7 , P10636-8 |
| Gene ID | 4137 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Tau 4R Rabbit mAb [67K76M08] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008] |
|---|
| Cellular Location | Cytoplasm Cytosol Cell membrane Peripheral membrane protein Cytoplasmic side Cytoplasm Cytoskeleton Cell projection Axon Cell projection Dendrite Secreted Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components (PubMed:10747907). Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059). |
|---|
| Tissue Location | Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system. |
|---|
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