Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R016126 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
![Anti-PKA RII alpha Rabbit mAb [73N94I80]](https://files.epizyme.cn:5005/uploads/products/202601/R016126-1.png)
![Anti-PKA RII alpha Rabbit mAb [73N94I80]](https://files.epizyme.cn:5005/uploads/products/202601/R016126-2.png)
![Anti-PKA RII alpha Rabbit mAb [73N94I80]](https://files.epizyme.cn:5005/uploads/products/202601/R016126-3.png)
| Product Name | Anti-PKA RII alpha Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, IHC-P/IF (Tissue-P), ELISA |
| Dilution | WB 1:1,000~1:2,000; IHC-P 1:100~1:200; IF 1:100~1:200 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 73N94I80 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthesized peptide derived from human PKA R2 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | PKA R2 (phospho-Ser96); phospho-PKA R2 (Ser96); phospho-PKA R2 (Ser99); KAP2; KAP2_HUMAN; MGC3606; PKR 2; PKR2; PRKA R2; PRKAR 2; PRKAR2; PRKAR2A; Protein kinase A RII alpha subunit; Protein kinase cAMP dependent regulatory type II alpha; cAMP dependent protein kinase regulatory subunit alpha 2; cAMP dependent protein kinase regulatory subunit RII alpha; cAMP dependent protein kinase type II alpha regulatory chain; cAMP dependent protein kinase type II alpha regulatory subunit; cAMP-dependent protein kinase type II-alpha regulatory subunit; phospho-PKA R2 (Ser98)(human). |
|---|---|
| Molecular weight | Calculated MW: 46 kDa; Observed MW: 50 kDa |
| Uniprot ID | P13861 |
| Gene ID | 5576 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-PKA RII alpha Rabbit mAb [73N94I80] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER). [provided by RefSeq, Jul 2008] |
|---|
| Cellular Location | Cytoplasm Cell membrane Colocalizes with PJA2 in the cytoplasm and the cell membrane. |
|---|
| Tissue Location | Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible. |
|---|
总篇数：加载中...
总影响因子：加载中...
最高影响因子：加载中...
上海市闵行区新骏环路760号1号楼3层
400-058-8030
技术支持(电话/微信)：
张老师 18217238522
罗老师 15021027255
李老师 18301721288
如有任何关于雅酶产品问题
欢迎来信咨询
雅酶微信公众号
Copyright © 2023上海雅酶生物医药科技有限公司（Epizyme Biotech）
沪ICP备2021002422号
