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Anti-Phospho-c-Myc (Thr58) Rabbit mAb [15T57G87]

Purified Recombinant Rabbit Monoclonal Antibody

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货号 规格 价格
R016105
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-Phospho-c-Myc (Thr58) Rabbit mAb [15T57G87]
Product NameAnti-Phospho-c-Myc (Thr58) Rabbit mAb
DescriptionPurified Recombinant Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ELISA
DilutionWB 1:1,000~1:2,000
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityMonoclonal
Clone No.15T57G87
IsotypeIgG
LabelUnconjugated
ImmunogenA synthesized peptide derived from human Phospho-c-Myc (T58)
FormatAffinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsMRTL; MYCC; bHLHe39; c-Myc; Myc2; Niard; Nird; RNCMYC; mMyc; MYC_HUMAN; MYC; Class E basic helix-loop-helix protein 39 (bHLHe39); Proto-oncogene c-Myc; Transcription factor p64; MYC_MOUSE; MYC_RAT.
Molecular weightCalculated MW: 51 kDa; Observed MW: 57 kDa
Uniprot ID P01106
Gene ID 4609
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-Phospho-c-Myc (Thr58) Rabbit mAb [15T57G87] is for research use only and not for use in diagnostic or therapeutic procedures.
Background This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
Cellular Location Nucleus Nucleoplasm Nucleus Nucleolus Nucleus Cytoplasm Localization to the nucleolus is dependent on HEATR1.

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