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Anti-Phospho-CDK7 (Thr170) Rabbit mAb [32C81P97]

Purified Recombinant Rabbit Monoclonal Antibody

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货号 规格 价格
R016051
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-Phospho-CDK7 (Thr170) Rabbit mAb [32C81P97]
Product NameAnti-Phospho-CDK7 (Thr170) Rabbit mAb
DescriptionPurified Recombinant Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ELISA
DilutionWB 1:1,000~1:2,000
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityMonoclonal
Clone No.32C81P97
IsotypeIgG
LabelUnconjugated
ImmunogenA synthetic phosphopeptide corresponding to residues surrounding Thr170 of human Cdk7
FormatAffinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsCDK7 (p-T170); p-CDK7; phospho-CDK7; CAK; CAK1; CDKN7; HCAK; MO15; STK1; p39MO15; CDK7_HUMAN; CDK7; 39 kDa protein kinase (p39 Mo15); CDK-activating kinase 1; Cell division protein kinase 7; Serine/threonine-protein kinase 1; TFIIH basal transcription factor complex kinase subunit; 2.7.11.22; 2.7.11.23.
Molecular weightCalculated MW: 39 kDa; Observed MW: 39 kDa
Uniprot ID P50613
Gene ID 1022
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-Phospho-CDK7 (Thr170) Rabbit mAb [32C81P97] is for research use only and not for use in diagnostic or therapeutic procedures.
Background The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]
Cellular Location Nucleus Cytoplasm Cytoplasm Perinuclear region Colocalizes with PRKCI in the cytoplasm and nucleus (PubMed:15695176). Translocates from the nucleus to cytoplasm and perinuclear region in response to DNA-bound peptides (PubMed:19071173).
Tissue Location Ubiquitous.

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