Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R016050 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-Phospho-Dishevelled 2 (Thr224) Rabbit mAb [70B07F41]](https://cdn.epizyme.cn/uploads/products/202601/R016050-1.png?v=20260109155522)
| Product Name | Anti-Phospho-Dishevelled 2 (Thr224) Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:3,000 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 70B07F41 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Thr224 of human Dishevelled 2 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | DVL2 | Dishevelled 2 (p-T224); p-Dishevelled 2; phospho-Dishevelled 2; Dvl-2; DVL2_HUMAN; DVL2; Dishevelled-2; DSH homolog 2; DVL2_MOUSE. |
|---|---|
| Molecular weight | Calculated MW: 79 kDa; Observed MW: 90-95 kDa |
| Uniprot ID | O14641 |
| Gene ID | 1856 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Phospho-Dishevelled 2 (Thr224) Rabbit mAb [70B07F41] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq, Jul 2008] |
|---|
| Cellular Location | Cell membrane Peripheral membrane protein Cytoplasmic side Cytoplasm Cytosol Cytoplasmic vesicle Nucleus Localizes at the cell membrane upon interaction with frizzled family members and promotes their internalization. Localizes to cytoplasmic puncta (By similarity). Interaction with FOXK1 and FOXK2 induces nuclear translocation (PubMed:25805136). |
|---|
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