Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R015969 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
![Anti-IRAK3 Rabbit mAb [64S18B87]](https://files.epizyme.cn:5005/uploads/products/202512/R015969-1.png)
| Product Name | Anti-IRAK3 Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 64S18B87 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthesized peptide derived from human IRAKM |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | Interleukin-1 receptor-associated kinase 3; IRAK-3; IL-1 receptor-associated kinase M; Inactive IL-1 receptor-associated kinase 3; IRAK-M; IRAK3. |
|---|---|
| Molecular weight | Calculated MW: 68 kDa; Observed MW: 68 kDa |
| Uniprot ID | Q9Y616 |
| Gene ID | 11213 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-IRAK3 Rabbit mAb [64S18B87] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
|---|
| Cellular Location | Cytoplasm Nucleus In dendritic cells, translocates into the nucleus upon IL33 stimulation |
|---|
| Tissue Location | Expressed in eosinophils, dendritic cells and/or monocytes (at protein level) (PubMed:29686383). Expressed predominantly in peripheral blood lymphocytes (PubMed:10383454) |
|---|
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