Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R015928 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-FADD Rabbit mAb [23E44D72]](https://files.epizyme.cn:5005/uploads/products/202511/R015928-1.png)
![Anti-FADD Rabbit mAb [23E44D72]](https://files.epizyme.cn:5005/uploads/products/202511/R015928-2.png)
| Product Name | Anti-FADD Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, IHC-P/IF (Tissue-P), ELISA |
| Dilution | WB 1:1,000~1:2,000; IHC-P 1:100~1:200; IF 1:100~1:200 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 23E44D72 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant protein of full length human FADD |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | MORT1; GIG3; FADD; FAS-associated death domain protein; FAS-associating death domain-containing protein; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity. |
|---|---|
| Molecular weight | Calculated MW: 23 kDa; Observed MW: 23 kDa |
| Uniprot ID | Q13158 |
| Gene ID | 8772 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-FADD Rabbit mAb [23E44D72] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008] |
|---|
| Tissue Location | Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes. |
|---|
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