Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R015882 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-Ras Rabbit mAb [28P24A51]](https://files.epizyme.cn:5005/uploads/products/202510/R015882-1.png)
![Anti-Ras Rabbit mAb [28P24A51]](https://files.epizyme.cn:5005/uploads/products/202510/R015882-2.png)
| Product Name | Anti-Ras Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 28P24A51 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthesized peptide derived from human KRAS+HRAS+NRAS |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | HRAS1; HRAS; GTPase HRas; H-Ras-1; Ha-Ras; Transforming protein p21; c-H-ras; p21ras. |
|---|---|
| Molecular weight | Calculated MW: 21.22 kDa; Observed MW: 21.22 kDa |
| Uniprot ID | P01111 , P01112 , P01116 |
| Gene ID | 4893 , 3265 , 3845 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Ras Rabbit mAb [28P24A51] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011] |
|---|
| Cellular Location | Cell membrane.Lipid-anchor.Cytoplasmic side.Golgi apparatus.Golgi apparatus membrane.Lipid-anchor.The active GTP-bound form is localized most strongly to membranes than the inactive GDP-bound form (By similarity). Shuttles between the plasma membrane and the Golgi apparatus..Isoform 2.Nucleus.Cytoplasm.Cytoplasm.Perinuclear region.Colocalizes with RACK1 to the perinuclear region. |
|---|
| Tissue Location | Widely expressed. |
|---|
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