Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R015808 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-Phospho-Synapsin I (Ser553) Rabbit mAb [66E88F55]](https://files.epizyme.cn:5005/uploads/products/202510/R015808-1.png)
![Anti-Phospho-Synapsin I (Ser553) Rabbit mAb [66E88F55]](https://files.epizyme.cn:5005/uploads/products/202510/R015808-2.png)
![Anti-Phospho-Synapsin I (Ser553) Rabbit mAb [66E88F55]](https://files.epizyme.cn:5005/uploads/products/202510/R015808-3.png)
| Product Name | Anti-Phospho-Synapsin I (Ser553) Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, IHC-P/IF (Tissue-P), ELISA |
| Dilution | WB 1:1,000~1:2,000; IHC-P 1:100~1:200; IF 1:100~1:200 |
| Reactivity | Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 66E88F55 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser553 of human Synapsin I |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | Synapsin-1; Brain protein 4.1; Synapsin I; SYN1; ; Syn-1; Syn1; Synapsin-1; Synapsin I; ; Synapsin-1; Synapsin I; Syn1. |
|---|---|
| Molecular weight | Calculated MW: 74 kDa; Observed MW: 77 kDa |
| Uniprot ID | P17600 , O88935 , P09951 |
| Gene ID | 6853 , 20964 , 24949 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Phospho-Synapsin I (Ser553) Rabbit mAb [66E88F55] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
|---|
| Cellular Location | Synapse.Golgi apparatus.Presynapse.Cytoplasmic vesicle.Secretory vesicle.Synaptic vesicle.Dissociates from synaptic vesicles and redistributes into the axon during action potential firing, in a step that precedes fusion of vesicles with the plasma membrane. Reclusters to presynapses after the cessation of synaptic activity. |
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