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Anti-FOXO4 Rabbit mAb [21J01H31]

Purified Recombinant Rabbit Monoclonal Antibody

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货号 规格 价格
R015787
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-FOXO4 Rabbit mAb [21J01H31]
Product NameAnti-FOXO4 Rabbit mAb
DescriptionPurified Recombinant Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ELISA
DilutionWB 1:1,000~1:2,000
ReactivityHuman
HostRabbit
ClonalityMonoclonal
Clone No.21J01H31
IsotypeIgG
LabelUnconjugated
ImmunogenA synthesized peptide derived from human FoxO4
FormatAffinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsAFX; AFX1; MLLT7; FOXO4; Forkhead box protein O4; Fork head domain transcription factor AFX1.
Molecular weightCalculated MW: 54 kDa; Observed MW: 54 kDa
Uniprot ID P98177
Gene ID 4303
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-FOXO4 Rabbit mAb [21J01H31] is for research use only and not for use in diagnostic or therapeutic procedures.
Background This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Cellular Location Cytoplasm.Nucleus.When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation. Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm.
Tissue Location Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Isoform zeta is most abundant in the liver, kidney, and pancreas.

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