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Anti-xCT Rabbit mAb [28R64J15]

Purified Recombinant Rabbit Monoclonal Antibody

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货号 规格 价格
R015754
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-xCT Rabbit mAb [28R64J15]
Product NameAnti-xCT Rabbit mAb
DescriptionPurified Recombinant Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ELISA
DilutionWB 1:1,000~1:2,000
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityMonoclonal
Clone No.28R64J15
IsotypeIgG
LabelUnconjugated
ImmunogenA synthesized peptide derived from human xCT
FormatAffinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsAmino acid transport system xc xCT antibody; Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; Calcium channel blocker resistance protein CCBR1 antibody; CCBR1; Cysteine/glutamate transporter antibody; Cystine/glutamate transporter; OTTHUMP00000164578; SLC7A11; Solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; solute carrier family 7; Solute carrier family 7 member 11; Solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; SYSTEM Xc(-) TRANSPORTER-RELATED PROTEIN; xCT; XCT_HUMAN.
Molecular weightCalculated MW: 55 kDa; Observed MW: 55 kDa
Uniprot ID Q9UPY5
Gene ID 23657
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-xCT Rabbit mAb [28R64J15] is for research use only and not for use in diagnostic or therapeutic procedures.
Background This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
Cellular Location Membrane.

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