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Anti-DRP1 Rabbit mAb [36G02G45]

Purified Recombinant Rabbit Monoclonal Antibody

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货号 规格 价格
R015603
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-DRP1 Rabbit mAb [36G02G45]
Anti-DRP1 Rabbit mAb [36G02G45]
Anti-DRP1 Rabbit mAb [36G02G45]
Product NameAnti-DRP1 Rabbit mAb
DescriptionPurified Recombinant Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P/IF (Tissue-P), ELISA
DilutionWB 1:1,000~1:2,000; IHC-P 1:100~1:200; IF 1:100~1:200
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityMonoclonal
Clone No.36G02G45
IsotypeIgG
LabelUnconjugated
ImmunogenRecombinant protein of mouse DRP1
FormatAffinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3.
SynonymsDLP1; dnm1l; DNM1L_HUMAN; Dnm1p/Vps1p-like protein; dnml1; DRP1; DVLP; Dymple; Dynamin 1 like; Dynamin family member proline-rich carboxyl-terminal domain less; Dynamin like protein; Dynamin related protein 1; Dynamin-1-like protein; Dynamin-like protein 4; Dynamin-like protein; Dynamin-like protein IV; Dynamin-related protein 1; DYNIV 11; EMPF; EMPF1; FLJ41912; HdynIV; VPS1.
Molecular weightCalculated MW: 82 kDa; Observed MW: 82 kDa
Uniprot ID Q8K1M6
Gene ID 74006
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-DRP1 Rabbit mAb [36G02G45] is for research use only and not for use in diagnostic or therapeutic procedures.
Background This gene encodes a member of the dynamin family. The encoded protein is localized to the cytoplasm and mitochondrial membrane, is involved in mitochondrial and peroxisomal division, and is essential for mitochondrial fission. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 2. [provided by RefSeq, Feb 2013]
Cellular Location Cytoplasm > cytosol. Golgi apparatus. Endomembrane system. Mainly cytosolic. Translocated to the mitochondrial membrane through interaction with FIS1. Colocalized with MARCH5 at mitochondrial membrane. Localizes to mitochondria at sites of division. Associated with peroxisomal membranes, partly recruited there by PEX11B. May also be associated with endoplasmic reticulum tubules and cytoplasmic vesicles and found to be perinuclear. In some cell types, localizes to the Golgi complex.
Tissue Location Ubiquitously expressed with highest levels found in skeletal muscles, heart, kidney and brain. Isoform 1 is brain-specific. Isoform 2 and isoform 3 are predominantly expressed in testis and skeletal muscles respectively. Isoform 4 is weakly expressed in brain, heart and kidney. Isoform 5 is dominantly expressed in liver, heart and kidney. Isoform 6 is expressed in neurons.

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