Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R015345 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-Phospho-AKT1 (Ser473)/AKT2 (Ser474)/AKT3 (Ser472) Rabbit mAb [30P57N10]](https://files.epizyme.cn:5005/uploads/products/202507/R015345-1.png)
| Product Name | Anti-Phospho-AKT1 (Ser473)/AKT2 (Ser474)/AKT3 (Ser472) Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 30P57N10 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser472 of human AKT3 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | AKT; AKT1; AKT1 kinase; AKT1m; AKT2; AKT2 kinase; Akt3; AKT3_HUMAN; CAKT; CWS6; DKFZp434N0250; HIHGHH; kinase Akt1; MGC99656; MPPH; Murine thymoma viral (v-akt) homolog 2; pan-akt; PKB ALPHA; PKB; PKB beta; PKB gamma; PKB-GAMMA; PKB/Akt; PKBALPHA; PKBB; PKBBETA; PKBG; PKBGAMMA; PRKBA; PRKBB; PRKBG; Protein kinase Akt 2; Protein kinase Akt-2; Protein kinase Akt-3; Protein kinase B alpha; Protein kinase B; Protein kinase B beta; Protein kinase B gamma; Proto oncogene c Akt; Proto-oncogene c-Akt; RAC ALPHA; RAC alpha serine/threonine protein kinase; RAC; RAC BETA; RAC beta serine/threonine protein kinase; RAC PK alpha; RAC PK beta; rac protein kinase alpha; rac protein kinase beta; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RAC-beta serine/threonine-protein kinase; RAC-gamma; RAC-gamma serine/threonine-protein kinase; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; RACALPHA; RACalpha serine/threonine kinase; RACBETA; RACgamma; RACgamma serine/threonine protein kinase; RACPKgamma; serine threonine protein kinase; STK 2; STK-2; STK2; thymoma viral proto oncogene 1; thymoma viral proto oncogene; V akt murine thymoma viral oncogene homolog 1; V akt murine thymoma viral oncogene homolog 2; V akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma); V akt murine thymoma viral oncogene homolog 3; V-AKT murine thymoma viral oncogene homolog 1; V-AKT murine thymoma viral oncogene homolog 2; V-AKT murine thymoma viral oncogene homolog 3; vakt murine thymoma viral oncogene homolog 1; vakt murine thymoma viral oncogene homolog 2; vakt murine thymoma viral oncogene homolog 3. |
|---|---|
| Molecular weight | Calculated MW: 56 kDa; Observed MW: 56 kDa |
| Uniprot ID | Q9Y243 |
| Gene ID | 10000 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Phospho-AKT1 (Ser473)/AKT2 (Ser474)/AKT3 (Ser472) Rabbit mAb [30P57N10] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] |
|---|
| Cellular Location | Cytoplasm. Membrane. Membrane-associated after cell stimulation leading to its translocation. |
|---|
| Tissue Location | In adult tissues, it is highly expressed in brain, lung and kidney, but weakly in heart, testis and liver. In fetal tissues, it is highly expressed in heart, liver and brain and not at all in kidney. |
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