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Anti-GABBR2 Rabbit mAb [66C46I94]

Purified Recombinant Rabbit Monoclonal Antibody

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货号 规格 价格
R015282
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-GABBR2 Rabbit mAb [66C46I94]
Anti-GABBR2 Rabbit mAb [66C46I94]
Product NameAnti-GABBR2 Rabbit mAb
DescriptionPurified Recombinant Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
 WB, IF (Cell)/ICC, ELISA
DilutionWB 1:1,000~1:2,000; IF 1:100~1:200
ReactivityMouse, Rat
HostRabbit
ClonalityMonoclonal
Clone No.66C46I94
IsotypeIgG
LabelUnconjugated
ImmunogenA synthesized peptide derived from human GABA B Receptor 2
FormatAffinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3.
SynonymsBcDNA GH07312; CG6706; CT20836; D Gaba2; FLJ36928; G protein coupled receptor 51; G protein coupled receptor 51; GAB B R2; GABA B R2; GABA B receptor 2; GABA B receptor 2; GABA B R2; GABA BR2; GABAB R2; GABABR 2; GABABR2; GABB R2; GABBR 2; Gabbr2; GABR2 HUMAN; Gamma aminobutyric acid B receptor 2; Gamma aminobutyric acid GABA B receptor 2; Gamma aminobutyric acid type B receptor subunit 2; Gamma aminobutyric acid type B receptor subunit 2; Gb 2; Gb2; GH07312; GPR 51; GPR51; GPRC 3B; GPRC3B; HG 20; HG20; HRIHFB2099; Metabotropic GABA B receptor subtype 2; OTTHUMP00000021776; OTTHUMP00000063797; R2 SUBUNIT.
Molecular weightCalculated MW: 106 kDa; Observed MW: 106 kDa
Uniprot ID O75899
Gene ID 9568
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-GABBR2 Rabbit mAb [66C46I94] is for research use only and not for use in diagnostic or therapeutic procedures.
Background The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010]
Cellular Location Cell membrane. Cell junction > synapse > postsynaptic cell membrane. Moreover coexpression of GABA-B-R1 and GABA-B-R2 appears to be a prerequisite for maturation and transport of GABA-B-R1 to the plasma membrane.
Tissue Location Highly expressed in brain, especially in cerebral cortex, thalamus, hippocampus, frontal, occipital and temporal lobe, occipital pole and cerebellum, followed by corpus callosum, caudate nucleus, spinal cord, amygdala and medulla. Weakly expressed in heart, testis and skeletal muscle.

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