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Anti-MCAK Rabbit mAb [34H15G55]

Purified Recombinant Rabbit Monoclonal Antibody

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货号 规格 价格
R015239
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-MCAK Rabbit mAb [34H15G55]
Product NameAnti-MCAK Rabbit mAb
DescriptionPurified Recombinant Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
 WB, ELISA
DilutionWB 1:1,000~1:2,000
ReactivityHuman
HostRabbit
ClonalityMonoclonal
Clone No.34H15G55
IsotypeIgG
LabelUnconjugated
ImmunogenA synthesized peptide derived from human MCAK
FormatAffinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3.
Synonyms4930402F02Rik; CT139; ESTM5; KIF 2C; kif2c; KIF2C_HUMAN; Kinesein Family Member 2C; Kinesin family member 2C; kinesin like 6 (mitotic centromere associated kinesin); Kinesin like 6; Kinesin like protein 6; Kinesin like protein KIF2C; Kinesin-like protein 6; Kinesin-like protein KIF2C; KNS L6; KNSL 6; KNSL6; MCAK; MGC11883; Mitotic centromere associated kinesin; Mitotic centromere-associated kinesin; OTTHUMP00000010066; X83316.
Molecular weightCalculated MW: 81 kDa; Observed MW: 81 kDa
Uniprot ID Q99661
Gene ID 11004
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-MCAK Rabbit mAb [34H15G55] is for research use only and not for use in diagnostic or therapeutic procedures.
Background This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Cellular Location Cytoplasm > cytoskeleton. Nucleus. Chromosome > centromere. Chromosome > centromere > kinetochore. Associates with the microtubule network at the growing distal tip (the plus-end) of microtubules, probably through interaction with MTUS2/TIP150 and MAPRE1 (By similarity). Centromeric localization requires the presence of BUB1 and SGOL2.
Tissue Location Expressed at high levels in thymus and testis, at low levels in small intestine, the mucosal lining of colon, and placenta, and at very low levels in spleen and ovary; expression is not detected in prostate, peripheral blood Leukocytes, heart, brain, lung, liver, skeletal muscle, kidney or pancreas. Isoform 2 is testis-specific.

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