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Anti-Lyn Rabbit mAb [54J29I60]

Purified Recombinant Rabbit Monoclonal Antibody

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货号 规格 价格
R015139
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-Lyn Rabbit mAb [54J29I60]
Product NameAnti-Lyn Rabbit mAb
DescriptionPurified Recombinant Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ELISA
DilutionWB 1:1,000~1:2,000
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityMonoclonal
Clone No.54J29I60
IsotypeIgG
LabelUnconjugated
ImmunogenA synthesized peptide derived from human Lyn
FormatAffinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3.
SynonymsAA407514, EC 2.7.10.2, FLJ26625, Hck 2, JTK 8, JTK8, Lck/Yes related novel protein tyrosine kinase, LYN, LYN proto oncogene, Src family tyrosine kinase, LYN_HUMAN, ONCOGENE LYN, p53Lyn, p56Lyn, Tyrosine protein kinase LYN, Tyrosine-protein kinase Lyn, V yes 1 Yamaguchi sarcoma viral related oncogene homolog, Yamaguchi sarcoma viral (v yes 1) related oncogene homolog.
Molecular weightCalculated MW: 59 kDa; Observed MW: 59 kDa
Uniprot ID P07948
Gene ID 4067
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-Lyn Rabbit mAb [54J29I60] is for research use only and not for use in diagnostic or therapeutic procedures.
Background This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Cellular Location Cell membrane. Nucleus. Cytoplasm. Cytoplasm > perinuclear region. Golgi apparatus. Accumulates in the nucleus by inhibition of CRM1-mediated nuclear export. Nuclear accumulation is increased by inhibition of its kinase activity. The trafficking from the Golgi apparatus to the plasma membrane occurs in a kinase domain-dependent but kinase activity independent manner and is mediated by exocytic vesicular transport.
Tissue Location Widely expressed in a variety of organs, tissues, and cell types such as epidermoid, hematopoietic, and neuronal cells. Expressed in primary neuroblastoma tumors.

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