Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R015040 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
| Product Name | Anti-APPL Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, IHC-P/IF (Tissue-P), ELISA |
| Dilution | WB 1:1,000~1:2,000; IHC-P 1:100~1:200; IF 1:100~1:200 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 36G47Q69 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthesized peptide derived from human APPL |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | Adapter protein containing PH domain, Adaptor Protein Containing pH Domain, Adaptor protein containing pH domain PTB domain and leucine zipper motif 1, Adaptor protein containing pH domain PTB domain and leucine zipper motif, Adaptor protein phosphotyrosine interacting with PH domain and leucine zipper 1, AKT2 INTERACTOR, APPL 1, Appl1, DCC interacting protein 13 alpha, DCC-interacting protein 13-alpha, DIP 13 alpha, DIP13 alpha, Dip13-alpha, DIP13alpha, DP13A_HUMAN, KIAA1428, PTB domain and leucine zipper motif 1, PTB Domain and Leucine Zipper Motif, Signaling adaptor protein DIP13alpha. |
|---|---|
| Molecular weight | Calculated MW: 80 kDa; Observed MW: 85 kDa |
| Uniprot ID | Q9UKG1 |
| Gene ID | 26060 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-APPL Rabbit mAb [36G47Q69] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008] |
|---|
| Cellular Location | Early endosome membrane. Nucleus. Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF. |
|---|
| Tissue Location | High levels in heart, ovary, pancreas and skeletal muscle. |
|---|
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总影响因子:加载中...
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