Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R014890 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
![Anti-Phospho-Bad (Ser112) Rabbit mAb [22A67Q16]](https://files.epizyme.cn:5005/uploads/productimage/R014890-1.png)
![Anti-Phospho-Bad (Ser112) Rabbit mAb [22A67Q16]](https://files.epizyme.cn:5005/uploads/productimage/R014890-2.png)
![Anti-Phospho-Bad (Ser112) Rabbit mAb [22A67Q16]](https://files.epizyme.cn:5005/uploads/productimage/R014890-3.png)
| Product Name | Anti-Phospho-Bad (Ser112) Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, IHC-P/IF (Tissue-P), ELISA |
| Dilution | WB 1:1,000~1:2,000; IHC-P 1:100~1:200; IF 1:100~1:200 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 22A67Q16 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthesized peptide derived from human Bad |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | AI325008, BAD, BAD_HUMAN, BBC 2, BBC2, BBC6, Bcl 2 Antagonist of Cell Death, Bcl 2 Binding Component 6, BCL X / BCL 2 Binding Protein, BCL X Binding Protein, Bcl XL/Bcl 2 Associated Death Promoter, Bcl-2-binding component 6, Bcl-2-like protein 8, Bcl-XL/Bcl-2-associated death promoter, Bcl2 antagonist of cell death, BCL2 antagonist of cell death protein, BCL2 associated agonist of cell death, Bcl2 Associated Death Promoter, BCL2 binding component 6, BCL2 binding protein, Bcl2 Like 8 Protein, Bcl2-L-8, BCL2L8, Proapoptotic BH3 Only Protein. |
|---|---|
| Molecular weight | Calculated MW: 18 kDa; Observed MW: 21 kDa |
| Uniprot ID | Q92934 |
| Gene ID | 572 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Phospho-Bad (Ser112) Rabbit mAb [22A67Q16] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Dec 2019] |
|---|
| Cellular Location | Mitochondrion outer membrane. Cytoplasm. Upon phosphorylation, locates to the cytoplasm. |
|---|
| Tissue Location | Expressed in a wide variety of tissues. |
|---|
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