Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R014871 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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| Product Name | Anti-IPL-1/STK13/Aurora C Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, IHC-P/IF (Tissue-P), ELISA |
| Dilution | WB 1:1,000~1:2,000; IHC-P 1:100~1:200; IF (Tissue-P) 1:50~1:100 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 61A09S85 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthesized peptide derived from human IPL-1/STK13/Aurora C |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | AURKC, AIE 2, Aie1, AIE2, AIK 3, AIK3, ARK 3, ARK-3, ARK3, Aur C, AurC, Aurkc, AURKC_HUMAN, aurora 3, Aurora C, Aurora kinase C, aurora related kinase 3, Aurora-related kinase 3, Aurora/Ipl1 related kinase 3, Aurora/Ipl1-related kinase 3, Aurora/Ipl1/Eg2 protein 2, EC 2.7.11.1, Serine threonine protein kinase 13, serine/threonine kinase 13 (aurora/IPL1 like), serine/threonine protein kinase aurora C, Serine/threonine-protein kinase 13, Serine/threonine-protein kinase aurora-C, SPGF5, STK13. |
|---|---|
| Molecular weight | Calculated MW: 36 kDa; Observed MW: 36 kDa |
| Uniprot ID | Q9UQB9 |
| Gene ID | 6795 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-IPL-1/STK13/Aurora C Rabbit mAb [61A09S85] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
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| Cellular Location | Chromosome. Cytoplasm > cytoskeleton > spindle. Distributes in the condensed chromosomes during prophase to metaphase. After entering anaphase, there is a dissociation from separated chromosomes and a redistribution to midzone microtubules, and finally remaines in the midbody during cytokinesis. |
|---|
| Tissue Location | Isoform 1 and isoform 2 are expressed in testis. Elevated expression levels were seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Expression is maximum at M phase. |
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