Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R014522 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
![Anti-Wnt5a Rabbit mAb [81L50M84]](https://files.epizyme.cn:5005/uploads/productimage/R014522-1.png)
![Anti-Wnt5a Rabbit mAb [81L50M84]](https://files.epizyme.cn:5005/uploads/productimage/R014522-2.png)
| Product Name | Anti-Wnt5a Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
ELISA, WB, IHC-P/IF (Tissue-P) |
| Dilution | WB 1:1,000~1:2,000; IHC-P 1:100~1:200; IF 1:100~1:200 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 81L50M84 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthesized peptide derived from human Wnt5a |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | hWNT 5A, hWNT5A, Protein Wnt 5a, Protein Wnt-5a, Protein Wnt5a, Wingless type MMTV integration site family member 5A, Wnt 5a, WNT 5A protein, WNT 5A protein precursor, WNT5A, WNT5A protein precursor, WNT5A_HUMAN. |
|---|---|
| Molecular weight | Calculated MW: 42 kDa; Observed MW: 45 kDa |
| Uniprot ID | P41221 |
| Gene ID | 7474 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Wnt5a Rabbit mAb [81L50M84] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. |
|---|
| Cellular Location | Secreted > extracellular space > extracellular matrix. |
|---|
| Tissue Location | Expression is increased in differentiated thyroid carcinomas compared to normal thyroid tissue and anaplastic thyroid tumors where expression is low or undetectable. Expression is found in thyrocytes but not in stromal cells (at protein level). |
|---|
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