Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R014517 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-LRP5 Rabbit mAb [54E24M17]](https://files.epizyme.cn:5005/uploads/productimage/R014517-1.png)
| Product Name | Anti-LRP5 Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 54E24M17 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant protein of human LRP5 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | BMND1, EVR1, EVR4, HBM, Low density lipoprotein receptor related protein 5, Low density lipoprotein receptor related protein 7, Low-density lipoprotein receptor-related protein 5, LR3, LRP-5, Lrp5, LRP5_HUMAN, LRP7, OPPG, OPS, OPTA1, Osteoporosis pseudoglioma syndrome, VBCH2. |
|---|---|
| Molecular weight | Calculated MW: 179 kDa; Observed MW: 200 kDa |
| Uniprot ID | O75197 |
| Gene ID | 4041 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-LRP5 Rabbit mAb [54E24M17] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
|---|
| Cellular Location | Membrane. Endoplasmic reticulum. Chaperoned to the plasma membrane by MESD. |
|---|
| Tissue Location | Widely expressed, with the highest level of expression in the liver. |
|---|
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