Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R014516 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-HtrA2/Omi Rabbit mAb [19D43C52]](https://files.epizyme.cn:5005/uploads/productimage/R014516-1.png)
![Anti-HtrA2/Omi Rabbit mAb [19D43C52]](https://files.epizyme.cn:5005/uploads/productimage/R014516-2.png)
![Anti-HtrA2/Omi Rabbit mAb [19D43C52]](https://files.epizyme.cn:5005/uploads/productimage/R014516-3.png)
| Product Name | Anti-HtrA2/Omi Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
IHC-P/IF (Tissue-P), WB, ELISA |
| Dilution | WB 1:1,000~1:5,000; IHC-P 1:100~1:200; IF 1:100~1:200 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 19D43C52 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthetic peptide of human HtrA2/Omi |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | High temperature requirement protein A2, HTRA 2, HtrA like serine protease, HtrA serine peptidase 2, HtrA, E. coli, homolog of, 2, HtrA2, HTRA2_HUMAN, mitochondrial, Omi stress regulated endoprotease, Omi stress-regulated endoprotease, PARK 13, PARK13, Protease serine 25, PRSS 25, PRSS25, Serine protease 25, Serine protease HTRA2, Serine protease HTRA2 mitochondrial, Serine protease htra2 mitochondrial precursor, Serine protease omi, Serine proteinase OMI. |
|---|---|
| Molecular weight | Calculated MW: 48 kDa; Observed MW: 36 kDa |
| Uniprot ID | O43464 |
| Gene ID | 27429 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-HtrA2/Omi Rabbit mAb [19D43C52] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016] |
|---|
| Cellular Location | Mitochondrion intermembrane space. Mitochondrion membrane. Predominantly present in the intermembrane space. Released into the cytosol following apoptotic stimuli, such as UV treatment, and stimulation of mitochondria with caspase-8 truncated BID/tBID. |
|---|
| Tissue Location | Isoform 1 is ubiquitous. Isoform 2 is expressed predominantly in the kidney, colon and thyroid. |
|---|
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