Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R014459 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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| Product Name | Anti-SFRP1 Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 69B22F54 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthesized peptide derived from human SFRP1 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | Frizzled related protein 1, FRP 1, FRP, FRP-1, FRP1, FrzA, SARP 2, SARP-2, SARP2, Secreted apoptosis related protein 2, Secreted apoptosis-related protein 2, Secreted frizzled related protein 1, Secreted frizzled related protein, Secreted frizzled-related protein 1, SFRP 1, sFRP-1, SFRP1, SFRP1_HUMAN. |
|---|---|
| Molecular weight | Calculated MW: 35 kDa; Observed MW: 35 kDa |
| Uniprot ID | Q8N474 |
| Gene ID | 6422 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-SFRP1 Rabbit mAb [69B22F54] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | SFRP proteins appear to act as tumor suppressors, with loss of expression or function correlating with many invasive forms of cancer. Deletion of the corresponding SFRP1 gene and promoter hypermethylation leading to gene silencing has been reported in a number of cancers. Abnormal expression of SRFP1 and other Wnt signaling proteins is associated with some cases of retinitis pigmentosa. |
|---|
| Cellular Location | Secreted. Cell membrane or extracellular matrix-associated. Released by heparin-binding. |
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| Tissue Location | Widely expressed. Absent from lung, liver and peripheral blood leukocytes. Highest levels in heart and fetal kidney. Also expressed in testis, ovary, fetal brain and lung, leiomyomal cells, myometrial cells and vascular smooth muscle cells. Expressed in foreskin fibroblasts and in keratinocytes. |
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