Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R014169 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-Phospho-Filamin A (Ser1083) Rabbit mAb [46A84R59]](https://files.epizyme.cn:5005/uploads/productimage/R014169-1.png)
| Product Name | Anti-Phospho-Filamin A (Ser1083) Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
ELISA, WB |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 46A84R59 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser1083 of human Filamin A |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | ABP 280, ABP-280, Actin-binding protein 280, Alpha filamin, Alpha-filamin, APBX, CSBS, CVD1, Endothelial actin binding protein, Endothelial actin-binding protein, Filamin 1, Filamin A alpha, Filamin A, Filamin-1, Filamin-A, FLN, FLN-A, FLN1, FLNA, FLNA_HUMAN, FMD, MNS, NHBP, Non muscle filamin, Non-muscle filamin, OPD, OPD1, OPD2, XLVD, XMVD. |
|---|---|
| Molecular weight | Calculated MW: 281 kDa; Observed MW: 281 kDa |
| Uniprot ID | P21333 |
| Gene ID | 2316 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Phospho-Filamin A (Ser1083) Rabbit mAb [46A84R59] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009] |
|---|
| Cellular Location | Cytoplasm > cell cortex. Cytoplasm > cytoskeleton. |
|---|
| Tissue Location | Ubiquitous. |
|---|
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