Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R014071 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
![Anti-VAV1 Rabbit mAb [98R69A83]](https://files.epizyme.cn:5005/uploads/productimage/R014071-1.png)
| Product Name | Anti-VAV1 Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 98R69A83 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthesized peptide derived from human Vav proteins |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | 2810040F13Rik, A530094I06Rik, AA986410, AI847175, FLJ40431, GDP/GTP exchange factor VAV2, Guanine nucleotide exchange factor VAV2, Guanine nucleotide exchange factor VAV3, MGC27838, Oncogene VAV, Oncogene VAV1, Oncogene VAV2, Oncogene VAV3, p95, p95vav, Protein vav 1, Protein vav 2, Protein vav 3, Proto oncogene vav, RGD1565941, VAV, vav 1 guanine nucleotide exchange factor, Vav 1 oncogene, vav 2 guanine nucleotide exchange factor, Vav 2 oncogene, vav 3 guanine nucleotide exchange factor, Vav 3 oncogene, vav-T, VAV1 oncogene, VAV2 oncogene, VAV3 oncogene. |
|---|---|
| Molecular weight | Calculated MW: 98 kDa; Observed MW: 98 kDa |
| Uniprot ID | P15498 |
| Gene ID | 7409 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-VAV1 Rabbit mAb [98R69A83] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012] |
|---|
| Cellular Location | Cytoplasmic and Plasma membrane VAV1, Cytoplasm - VAV2 & VAV3 |
|---|
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