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Anti-SIRT6 Rabbit mAb [11I90O50]

Purified Recombinant Rabbit Monoclonal Antibody

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货号 规格 价格
R014059
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-SIRT6 Rabbit mAb [11I90O50]
Product NameAnti-SIRT6 Rabbit mAb
DescriptionPurified Recombinant Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ELISA
DilutionWB 1:1,000~1:2,000
ReactivityHuman
HostRabbit
ClonalityMonoclonal
Clone No.11I90O50
IsotypeIgG
LabelUnconjugated
ImmunogenA synthesized peptide derived from human SIRT6
FormatAffinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3.
Synonyms2810449N18Rik, AI043036, Mono ADP ribosyltransferase sirtuin 6, NAD-dependent protein deacetylase sirtuin-6, Regulatory protein SIR2 homolog 6, Regulatory protein SIR2 homolog, SIR2 like 6, SIR2 like protein 6, Sir2 related protein type 6, SIR2-like protein 6, SIR2L6, SIR6_HUMAN, SIRT 6, SIRT6, Sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae), Sirtuin 6, Sirtuin type 6, Sirtuin6.
Molecular weightCalculated MW: 39 kDa; Observed MW: 42 kDa
Uniprot ID Q8N6T7
Gene ID 51548
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-SIRT6 Rabbit mAb [11I90O50] is for research use only and not for use in diagnostic or therapeutic procedures.
Background This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Cellular Location Nucleus, nucleoplasm. Predominantly nuclear. Associated with telomeric heterochromatin regions.

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