Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R014058 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
![Anti-SHP2 Rabbit mAb [69E66O87]](https://files.epizyme.cn:5005/uploads/productimage/R014058-1.png)
![Anti-SHP2 Rabbit mAb [69E66O87]](https://files.epizyme.cn:5005/uploads/productimage/R014058-2.png)
| Product Name | Anti-SHP2 Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, IF (Cell)/ICC, ELISA |
| Dilution | WB 1:1,000~1:2,000; IF 1:100~1:200 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 69E66O87 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant protein of mouse SHP2 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | BPTP3, CFC, JMML, METCDS, MGC14433, NS1, OTTHUMP00000166107, OTTHUMP00000166108, Protein tyrosine phosphatase 2, Protein tyrosine phosphatase 2C, Protein tyrosine phosphatase non receptor type 11, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, PTN11_HUMAN, PTP-1D, PTP-2C, PTP1D, PTP2C, PTPN11, SAP2, SH-PTP2, SH-PTP3, SH2 domain containing protein tyrosine phosphatase 2, SHP 2, SHP-2, Shp2, SHPTP2, SHPTP3, Syp, Tyrosine-protein phosphatase non-receptor type 11. |
|---|---|
| Molecular weight | Calculated MW: 68 kDa; Observed MW: 72 kDa |
| Uniprot ID | P35235 |
| Gene ID | 19247 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-SHP2 Rabbit mAb [69E66O87] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Enables cell adhesion molecule binding activity; protein tyrosine phosphatase activity; and signaling receptor binding activity. Involved in negative regulation of chondrocyte differentiation; positive regulation of cytokine production; and positive regulation of ossification. Acts upstream of or within several processes, including cell surface receptor signaling pathway; myeloid cell differentiation; and regulation of hormone secretion. Predicted to be located in several cellular components, including mitochondrion; plasma membrane raft; and stress fiber. Predicted to be part of protein-containing complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Used to study several diseases, including Noonan syndrome 1; Noonan syndrome with multiple lentigines; hepatocellular adenoma; intrinsic cardiomyopathy (multiple); and juvenile myelomonocytic leukemia. Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome (multiple); Noonan syndrome with multiple lentigines 1; atrophic gastritis; juvenile myelomonocytic leukemia; and metachondromatosis. Orthologous to human PTPN11 (protein tyrosine phosphatase non-receptor type 11). [provided by Alliance of Genome Resources, Apr 2022] |
|---|
| Cellular Location | Cytoplasm. |
|---|
| Tissue Location | Widely expressed, with highest levels in heart, brain, and skeletal muscle. |
|---|
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