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Anti-Myosin Light Chain 2 Rabbit mAb [30B12M39]

Purified Recombinant Rabbit Monoclonal Antibody

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货号 规格 价格
R013852
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-Myosin Light Chain 2 Rabbit mAb [30B12M39]
Anti-Myosin Light Chain 2 Rabbit mAb [30B12M39]
Product NameAnti-Myosin Light Chain 2 Rabbit mAb
DescriptionPurified Recombinant Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ELISA
DilutionWB 1:1,000~1:5,000
ReactivityMouse, Rat
HostRabbit
ClonalityMonoclonal
Clone No.30B12M39
IsotypeIgG
LabelUnconjugated
ImmunogenA synthesized peptide derived from human Myosin Light Chain 2
FormatAffinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3.
SynonymsMYL2, MLC2, Myosin light chain 2, MLC-2, RLC of myosin, CMH10, MLC-2v.
Molecular weightCalculated MW: 19 kDa; Observed MW: 19 kDa
Uniprot ID P10916
Gene ID 4633
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-Myosin Light Chain 2 Rabbit mAb [30B12M39] is for research use only and not for use in diagnostic or therapeutic procedures.
Background Defects in Myosin Light Chain 2 are the cause of cardiomyopathy familial hypertrophic type 10 (CMH10) [MIM:608758]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death. Defects in MYL2 are the cause of cardiomyopathy familial hypertrophic with mid-left ventricular chamber type 2 (MVC2) [MIM:608758]. MVC2 is a very rare variant of familial hypertrophic cardiomyopathy, characterized by mid-left ventricular chamber thickening.
Cellular Location Endoplasmic reticulum lumen. Melanosome. Cytoplasm. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

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