Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R013517 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
立即购买
![Anti-Activin Receptor Type IA Rabbit mAb [19K78K68]](https://files.epizyme.cn:5005/uploads/productimage/R013517-1.png)
| Product Name | Anti-Activin Receptor Type IA Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:3,000 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 19K78K68 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthesized peptide derived from human Activin Receptor Type IA |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | Activin A receptor type I, Activin A receptor type II like kinase 2, Activin receptor type I, Activin receptor type-1, Activin receptor-like kinase 2, ACTR-I, ACTRI, Acvr1, ACVR1_HUMAN, ACVR1A, ACVRLK2, ALK 2, ALK-2, ALK2, FOP, Hydroxyalkyl protein kinase, Serine/threonine-protein kinase receptor R1, SKR1, TGF-B superfamily receptor type I, TGFB superfamily receptor type I, TSR-I, TSRI. |
|---|---|
| Molecular weight | Calculated MW: 57 kDa; Observed MW: 57 kDa |
| Uniprot ID | Q04771 |
| Gene ID | 90 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Activin Receptor Type IA Rabbit mAb [19K78K68] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq, Jul 2008] |
|---|
| Cellular Location | Membrane. |
|---|
| Tissue Location | Expressed in normal parenchymal cells, endothelial cells, fibroblasts and tumor-derived epithelial cells. |
|---|
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