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Anti-MERTK Rabbit mAb [66L24M93]

Purified Rabbit Monoclonal Antibody

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货号 规格 价格
R013456
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-MERTK Rabbit mAb [66L24M93]
Anti-MERTK Rabbit mAb [66L24M93]
Product NameAnti-MERTK Rabbit mAb
DescriptionPurified Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P/IF (Tissue-P), IP, ELISA
DilutionWB 1:500~1:1,000; IHC-P 1:50~1:100; IP 1:20
ReactivityHuman
HostRabbit
ClonalityMonoclonal
Clone No.66L24M93
IsotypeIgG
LabelUnconjugated
ImmunogenA synthetic peptide of human MERTK
FormatBuffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified.
SynonymsMERTK, MER, Tyrosine-protein kinase Mer, Proto-oncogene c-Mer, Receptor tyrosine kinase MerTK.
Molecular weightCalculated MW: 110 kDa; Observed MW: 210 kDa
Uniprot ID Q12866
Gene ID 10461
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-MERTK antibody [66L24M93] is for research use only and not for use in diagnostic or therapeutic procedures.
Background MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

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