Purified Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R013007 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-Phospho-JNK1 (Thr183/Tyr185) Rabbit mAb [60M45L43]](https://files.epizyme.cn:5005/uploads/antybody/R013007_1.jpg)
| Product Name | Anti-Phospho-JNK1 (Thr183/Tyr185) Rabbit mAb |
|---|---|
| Description | Purified Rabbit Monoclonal Antibody |
Application
|
WB, IP, ELISA |
| Dilution | WB 1:500~1:1,000; IP 1:20 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 60M45L43 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Thr183/Tyr185 of human JNK1 |
| Format | Buffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified. |
| Synonyms | AI849689, c Jun N terminal kinase 1, C-JUN kinase 1, c-Jun N-terminal kinase 1, EC 271124, JAK 1A, JAK1A, JNK 1, JNK 46, JNK, JNK-46, JNK1A2, JNK21B1/2, MAP kinase 8, MAPK 8, MAPK8, Mitogen activated protein kinase 8, Mitogen-activated protein kinase 8, MK08_HUMAN, p54 gamma, PRKM 8, PRKM8, Protein kinase JNK1, Protein kinase, mitogen-activated, 8, SAPK 1, SAPK gamma, SAPK1, Stress activated protein kinase JNK1, Stress-activated protein kinase 1, Stress-activated protein kinase JNK1, Tyrosine protein kinase JAK1. |
|---|---|
| Molecular weight | Calculated MW: 48 kDa; Observed MW: 46,54 kDa |
| Uniprot ID | P45983 |
| Gene ID | 5599 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Phospho-JNK1 (Thr183/Tyr185) antibody [60M45L43] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016] |
|---|
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