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Anti-RAMP1 Rabbit mAb [98K44L90]

Purified Recombinant Rabbit Monoclonal Antibody

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货号 规格 价格
R012965
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-RAMP1 Rabbit mAb [98K44L90]
Product NameAnti-RAMP1 Rabbit mAb
DescriptionPurified Recombinant Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ELISA
DilutionWB 1:1,000~1:3,000
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityMonoclonal
Clone No.98K44L90
IsotypeIgG
LabelUnconjugated
ImmunogenA synthesized peptide derived from human RAMP1
FormatAffinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsReceptor activity-modifying protein 1; Calcitonin-receptor-like receptor activity-modifying protein 1; CRLR activity-modifying protein 1; RAMP1.
Molecular weightCalculated MW: 17 kDa; Observed MW: 21 kDa
Uniprot ID O60894
Gene ID 10267
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-RAMP1 Rabbit mAb [98K44L90] is for research use only and not for use in diagnostic or therapeutic procedures.
Background The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Cellular Location Cell membrane.Single-pass type I membrane protein.
Tissue Location Expressed in many tissues including the uterus, bladder, brain, pancreas and gastro-intestinal tract.

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