Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R012944 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-SLAMF6 Rabbit mAb [66M89M67]](https://files.epizyme.cn:5005/uploads/products/202511/R012944-1.png)
| Product Name | Anti-SLAMF6 Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 66M89M67 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant protein of human SLAMF6 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | CD352; KALI; UNQ6123/PRO20080; SLAMF6; SLAM family member 6; Activating NK receptor; NK-T-B-antigen; NTB-A. |
|---|---|
| Molecular weight | Calculated MW: 37 kDa; Observed MW: 60 kDa |
| Uniprot ID | Q96DU3 |
| Gene ID | 114836 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-SLAMF6 Rabbit mAb [66M89M67] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010] |
|---|
| Cellular Location | Cell membrane.Single-pass type I membrane protein. |
|---|
| Tissue Location | Expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes (PubMed:11489943). Increased surface expression on T-cells of systemic lupus erythematosus (SLE) patients (PubMed:22184727). |
|---|
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