Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R012931 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-ENO1/2/3 Rabbit mAb [99K55L22]](https://files.epizyme.cn:5005/uploads/productimage/R012931-1.png)
![Anti-ENO1/2/3 Rabbit mAb [99K55L22]](https://files.epizyme.cn:5005/uploads/productimage/R012931-2.png)
| Product Name | Anti-ENO1/2/3 Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, IF (Cell)/ICC, ELISA |
| Dilution | WB 1:1,000~1:2,000; IF 1:100~1:200 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 99K55L22 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant protein of human ENO1 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | 2-phospho-D-glycerate hydro-lyase, Alpha-enolase, Beta-enolase, C-myc promoter-binding protein, Crystallin Tau, included, ENO1L1, Enolase 1, (alpha), Enolase 2 (gamma, neuronal), Enolase 2, Enolase 3 (beta, muscle), Enolase 3, Enolase alpha, Enolase, beta, Enolase, gamma, Enolase, muscle specific, Enolase, neuron specific, Enolase, nonneuronal, included, Gamma-enolase, GSD13, MBP-1, MPB1, MSE, Muscle-specific enolase, Neural enolase, Neuron-specific enolase, NNE, Non-neural enolase, NSE, Phosphpyruvate hydratase, Plasminogen-binding protein, Skeletal muscle enolase. |
|---|---|
| Molecular weight | Calculated MW: 47 kDa; Observed MW: 47 kDa |
| Uniprot ID | P06733 |
| Gene ID | 2023 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-ENO1/2/3 antibody [99K55L22] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.MiscellaneousUsed as a diagnostic marker for many tumors and, in the heterodimeric form, alpha/gamma, as a marker for hypoxic brain injury after cardiac arrest. Also marker for endometriosis. Antibodies against alpha-enolase are present in sera from patients with cancer-associated retinopathy syndrome (CAR), a progressive blinding disease which occurs in the presence of systemic tumor growth, primarily small-cell carcinoma of the lung and other malignancies. Is identified as an autoantigen in Hashimoto encephalopathy (HE) a rare autoimmune disease associated with Hashimoto thyroiditis (HT). HT is a disorder in which destructive processes overcome the potential capacity of thyroid replacement leading to hypothyroidism. |
|---|
| Cellular Location | ENO1: Cytoplasm. Cell membrane. Cytoplasm, myofibril, sarcomere, M-band. Note: Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form. ENO1 is localized to the M-band. ENO2: Cytoplasm. Cell membrane. Note: Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form ENO3: Cytoplasm. Note: Localized to the Z line. Some colocalization with CKM at M-band. |
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