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Anti-PCPTP1 Rabbit mAb [13M73L21]

Purified Recombinant Rabbit Monoclonal Antibody

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货号 规格 价格
R012840
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-PCPTP1 Rabbit mAb [13M73L21]
Product NameAnti-PCPTP1 Rabbit mAb
DescriptionPurified Recombinant Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, ELISA
DilutionWB 1:1,000~1:2,000
ReactivityMouse, Rat
HostRabbit
ClonalityMonoclonal
Clone No.13M73L21
IsotypeIgG
LabelUnconjugated
ImmunogenA synthesized peptide derived from human PCPTP1
FormatAffinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsECPTP; PTPRQ; PTPRR; Receptor-type tyrosine-protein phosphatase R; R-PTP-R; Ch-1PTPase; NC-PTPCOM1; Protein-tyrosine phosphatase PCPTP1.
Molecular weightCalculated MW: 74 kDa; Observed MW: 74 kDa
Uniprot ID Q15256
Gene ID 5801
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-PCPTP1 Rabbit mAb [13M73L21] is for research use only and not for use in diagnostic or therapeutic procedures.
Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]
Cellular Location Secreted.Isoform Alpha.Cell membrane.Single-pass type I membrane protein.Isoform Delta.Cytoplasm.Perinuclear region.Locates to the perinuclear areas within the cytoplasm.Isoform Gamma.Cytoplasm.Perinuclear region.Locates to the perinuclear areas within the cytoplasm.
Tissue Location Detected in cerebrospinal fluid (at protein level) (PubMed:25326458). Expressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus.

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