Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R012707 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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| Product Name | Anti-Phospho-MSK1 (Ser360) Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 78K01M42 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser360 of human MSK1 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | RPS6KA5 | MSK1 (p-S360); p-MSK1; phospho-MSK1; MSK1; MSPK1; RLPK; 3110005L17Rik; 6330404E13Rik; RLSK; S6K-alpha-5; KS6A5_HUMAN; RPS6KA5; 90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen- and stress-activated protein kinase 1; RSK-like protein kinase (RSKL); 2.7.11.1; KS6A5_MOUSE; RSK-like protein kinase (RLSK). |
|---|---|
| Molecular weight | Calculated MW: 90 kDa; Observed MW: 90 kDa |
| Uniprot ID | O75582 |
| Gene ID | 9252 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Phospho-MSK1 (Ser360) Rabbit mAb [78K01M42] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. |
|---|
| Cellular Location | Nucleus Cytoplasm Predominantly nuclear. Exported into cytoplasm in response to glucocorticoid. |
|---|
| Tissue Location | Widely expressed with high levels in heart, brain and placenta. Less abundant in lung, kidney and liver. |
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