Purified Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R012565 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-Phospho-AKT1 (Thr450) Rabbit mAb [25L76M50]](https://files.epizyme.cn:5005/uploads/antybody/R012565_1.jpg)
| Product Name | Anti-Phospho-AKT1 (Thr450) Rabbit mAb |
|---|---|
| Description | Purified Rabbit Monoclonal Antibody |
Application
|
WB, IP, ELISA |
| Dilution | WB 1:500~1:1,000; IP 1:20 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 25L76M50 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Thr450 of human AKT1 |
| Format | Buffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified. |
| Synonyms | AKT1, PKB, RAC, RAC-alpha serine/threonine-protein kinase, Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha. |
|---|---|
| Molecular weight | Calculated MW: 56 kDa; Observed MW: 56 kDa |
| Uniprot ID | P31749 |
| Gene ID | 207 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Phospho-AKT1 (Thr450) antibody [25L76M50] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473. |
|---|
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