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Anti-Phospho-Raf1 (Ser259) Rabbit mAb [69L67L72]

Purified Rabbit Monoclonal Antibody

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货号 规格 价格
R012443
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-Phospho-Raf1 (Ser259) Rabbit mAb [69L67L72]
Anti-Phospho-Raf1 (Ser259) Rabbit mAb [69L67L72]
Product NameAnti-Phospho-Raf1 (Ser259) Rabbit mAb
DescriptionPurified Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P/IF (Tissue-P), ELISA
DilutionWB 1:500~1:1,000; IHC-P 1:50~1:100
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityMonoclonal
Clone No.69L67L72
IsotypeIgG
LabelUnconjugated
ImmunogenA synthetic phosphopeptide corresponding to residues surrounding Ser259 of human Raf1
FormatBuffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified.
SynonymsRAF1, RAF, RAF proto-oncogene serine/threonine-protein kinase, Proto-oncogene c-RAF, cRaf, Raf-1.
Molecular weightCalculated MW: 73 kDa; Observed MW: 73 kDa
Uniprot ID P04049
Gene ID 5894
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-Phospho-Raf1 (Ser259) antibody [69L67L72] is for research use only and not for use in diagnostic or therapeutic procedures.
Background Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2.

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