Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R012364 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-Axin 2 Rabbit mAb [71L62L64]](https://files.epizyme.cn:5005/uploads/productimage/R012364-1.png)
| Product Name | Anti-Axin 2 Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 71L62L64 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthesized peptide derived from human Axin 2 |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.01% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | Axil, Axin like protein, Axin-2, Axin-like protein, Axin2, AXIN2_HUMAN, Axis inhibition protein 2, Conductin, DKFZp781B0869, MGC10366, MGC126582. |
|---|---|
| Molecular weight | Calculated MW: 94 kDa; Observed MW: 94 kDa |
| Uniprot ID | Q9Y2T1 |
| Gene ID | 8313 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-Axin 2 Rabbit mAb [71L62L64] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair. [provided by RefSeq, Jul 2008] |
|---|
| Cellular Location | Cytoplasm. |
|---|
| Tissue Location | Expressed in brain and lymphoblast. |
|---|
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