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Anti-GSDME Rabbit mAb [85K48L39]

Purified Recombinant Rabbit Monoclonal Antibody

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货号 规格 价格
R012246
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-GSDME Rabbit mAb [85K48L39]
Anti-GSDME Rabbit mAb [85K48L39]
Product NameAnti-GSDME Rabbit mAb
DescriptionPurified Recombinant Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
 WB, IHC-P/IF (Tissue-P), ELISA
DilutionWB 1:1,000~1:2,000; IHC-P 1:100~1:200; IF 1:100~1:200
ReactivityHuman
HostRabbit
ClonalityMonoclonal
Clone No.85K48L39
IsotypeIgG
LabelUnconjugated
ImmunogenRecombinant protein of human DFNA5/GSDME
FormatAffinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsDFNA5; ICERE1; GSDME; Gasdermin-E; Inversely correlated with estrogen receptor expression 1; Non-syndromic hearing impairment protein 5; ICERE-1.
Molecular weightCalculated MW: 55 kDa; Observed MW: 55 kDa
Uniprot ID O60443
Gene ID 1687
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-GSDME Rabbit mAb [85K48L39] is for research use only and not for use in diagnostic or therapeutic procedures.
Background Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Cellular Location Gasdermin-E, N-terminal.Cell membrane.Multi-pass membrane protein.Gasdermin-E.Cytoplasm.Cytosol.
Tissue Location Expressed in cochlea (PubMed:9771715). Low level of expression in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas, with highest expression in placenta (PubMed:9771715).

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