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Anti-Prostaglandin E Synthase Rabbit mAb [66K36K48]

Purified Recombinant Rabbit Monoclonal Antibody

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货号 规格 价格
R012074
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-Prostaglandin E Synthase Rabbit mAb [66K36K48]
Product NameAnti-Prostaglandin E Synthase Rabbit mAb
DescriptionPurified Recombinant Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
 WB, ELISA
DilutionWB 1:1,000~1:2,000
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityMonoclonal
Clone No.66K36K48
IsotypeIgG
LabelUnconjugated
ImmunogenA synthesized peptide derived from human Prostaglandin E Synthase
FormatAffinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
SynonymsMGST1L1; MPGES1; PGES; PIG12; PTGES; Prostaglandin E synthase; Glutathione peroxidase PTGES; Glutathione transferase PTGES; Microsomal glutathione S-transferase 1-like 1; Microsomal prostaglandin E synthase 1; p53-induced gene 12 protein; MGST1-L1; MPGES-1.
Molecular weightCalculated MW: 17 kDa; Observed MW: 17 kDa
Uniprot ID O14684
Gene ID 9536
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-Prostaglandin E Synthase Rabbit mAb [66K36K48] is for research use only and not for use in diagnostic or therapeutic procedures.
Background The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008]
Cellular Location Membrane.Multi-pass membrane protein.Cytoplasm.Perinuclear region.Colocalizes with PTGS1/COX-1 and PTGS2/COX-2 in the perinuclear compartment.

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