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Anti-PCBP2 Rabbit mAb [14M60M45]

Purified Rabbit Monoclonal Antibody

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货号 规格 价格
R011906
20µL ¥588.00
50µL ¥1080.00
100µL ¥1780.00

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Anti-PCBP2 Rabbit mAb [14M60M45]
Product NameAnti-PCBP2 Rabbit mAb
DescriptionPurified Rabbit Monoclonal Antibody
Application
  • Applications Legend:
  • WB=Western Blotting
  • IHC-P=Immunohistochemistry (Paraffin)
  • IHC-F=Immunohistochemistry (Frozen)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IP, ELISA
DilutionWB 1:500~1:1,000; IP 1:20
ReactivityMouse, Rat
HostRabbit
ClonalityMonoclonal
Clone No.14M60M45
IsotypeIgG
LabelUnconjugated
ImmunogenA synthetic peptide of human PCBP2
FormatBuffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified.
SynonymsHNRPE2, HNRNPE2, hnRNP-E2.
Molecular weightCalculated MW: 39 kDa; Observed MW: 35-45 kDa
Uniprot ID Q15366
Gene ID 5094
StorageShipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage.
PrecautionsAnti-PCBP2 antibody [14M60M45] is for research use only and not for use in diagnostic or therapeutic procedures.
Background Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling (PubMed:19881509). It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation (PubMed:19881509).

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