Purified Recombinant Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R011715 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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![Anti-XIAP Rabbit mAb [41L25L98]](https://files.epizyme.cn:5005/uploads/products/202511/R011715-1.png)
| Product Name | Anti-XIAP Rabbit mAb |
|---|---|
| Description | Purified Recombinant Rabbit Monoclonal Antibody |
Application
|
WB, ELISA |
| Dilution | WB 1:1,000~1:2,000 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 41L25L98 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | Recombinant protein of human XIAP |
| Format | Affinity purified monoclonal antibody supplied in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Synonyms | Aipa; Api3; Birc4; Miha; Xiap; E3 ubiquitin-protein ligase XIAP; Baculoviral IAP repeat-containing protein 4; IAP homolog A; Inhibitor of apoptosis protein 3; RING-type E3 ubiquitin transferase XIAP; X-linked inhibitor of apoptosis protein; IAP-3; mIAP-3; mIAP3; X-linked IAP. |
|---|---|
| Molecular weight | Calculated MW: 57 kDa; Observed MW: 57 kDa |
| Uniprot ID | Q60989 |
| Gene ID | 11798 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-XIAP Rabbit mAb [41L25L98] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011] |
|---|
| Cellular Location | Cytoplasm.Nucleus.TLE3 promotes its nuclear localization. |
|---|
| Tissue Location | Expressed in small intestine crypts (at protein level) (PubMed:30389919). Expressed in bulge hair follicle stem cells, sebaceous glands and dermal papillae (at protein level) (PubMed:23788729). |
|---|
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