Purified Rabbit Monoclonal Antibody
| 货号 | 规格 | 价格 |
|---|---|---|
| R011679 | ||
| 20µL | ¥588.00 | |
| 50µL | ¥1080.00 | |
| 100µL | ¥1780.00 |
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| Product Name | Anti-PP2A alpha/beta Rabbit mAb |
|---|---|
| Description | Purified Rabbit Monoclonal Antibody |
Application
|
WB, IHC-F/IF (Tissue-F), IHC-P/IF (Tissue-P), ICC/IF (Cell), IP, ELISA |
| Dilution | WB 1:500~1:1,000; IHC-P 1:50~1:100; IF 1:50~1:200; IP 1:20 |
| Reactivity | Hamster, Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 68K98L03 |
| Isotype | IgG |
| Label | Unconjugated |
| Immunogen | A synthetic peptide of human PP2A alpha |
| Format | Buffer System: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA Purification: Affinity Purified. |
| Synonyms | PPP2CA, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha, Replication protein C, RP-C. |
|---|---|
| Molecular weight | Calculated MW: 36 kDa; Observed MW: 36 kDa |
| Uniprot ID | P67775 |
| Gene ID | 5515 |
| Storage | Shipped on wet ice. Store at -20℃. Stable for 24 months from date of receipt. Aliquoting is unnecessary for -20℃ storage. |
| Precautions | Anti-PP2A alpha/beta antibody [68K98L03] is for research use only and not for use in diagnostic or therapeutic procedures. |
| Background | PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'. |
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